Integrated analysis of mismatch repair system in malignant astrocytomas.

Integrated analysis of mismatch repair system in malignant astrocytomas.

Malignant astrocytomas are the most aggressive primary brain tumors with a poor prognosis despite optimal treatment. Dysfunction of mismatch repair (MMR) system accelerates the accumulation of mutations throughout the genome causing uncontrolled cell growth. The aim of this study was to characterize...

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Autores principales: Irene Rodríguez-Hernández, Juan Luis Garcia, Angel Santos-Briz, Aurelio Hernández-Laín, Jose María González-Valero, Juan Antonio Gómez-Moreta, Oscar Toldos-González, Juan Jesús Cruz, Javier Martin-Vallejo, Rogelio González-Sarmiento
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/22bad0908c5d4b80bab0b38397be9578
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https://doaj.org/article/22bad0908c5d4b80bab0b38397be9578

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