Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm.
<h4>Background</h4>Male-factor infertility is a common condition, and etiology is unknown for a high proportion of cases. Abnormal epigenetic programming of the germline is proposed as a possible mechanism compromising spermatogenesis of some men currently diagnosed with idiopathic infer...
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Main Authors: | Sahar Houshdaran, Victoria K Cortessis, Kimberly Siegmund, Allen Yang, Peter W Laird, Rebecca Z Sokol |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2007
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Online Access: | https://doaj.org/article/22c4699e7dba4875bc2049af3e3c75a2 |
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