Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes

Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes

Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerular capillaries of mice.

Saved in:
Bibliographic Details
Main Authors: Clare L. V. Westhorpe, M. Ursula Norman, Pam Hall, Sarah L. Snelgrove, Michaela Finsterbusch, Anqi Li, Camden Lo, Zhe Hao Tan, Songhui Li, Susan K. Nilsson, A. Richard Kitching, Michael J. Hickey
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
Q
Online Access:https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af

Similar Items