Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerular capillaries of mice.
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Nature Portfolio
2018
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oai:doaj.org-article:22e1efaabd3040d59c9272c8e00fd9af2021-12-02T16:49:50ZEffector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes10.1038/s41467-018-03181-42041-1723https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03181-4https://doaj.org/toc/2041-1723Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerular capillaries of mice.Clare L. V. WesthorpeM. Ursula NormanPam HallSarah L. SnelgroveMichaela FinsterbuschAnqi LiCamden LoZhe Hao TanSonghui LiSusan K. NilssonA. Richard KitchingMichael J. HickeyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q Clare L. V. Westhorpe M. Ursula Norman Pam Hall Sarah L. Snelgrove Michaela Finsterbusch Anqi Li Camden Lo Zhe Hao Tan Songhui Li Susan K. Nilsson A. Richard Kitching Michael J. Hickey Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes |
description |
Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerular capillaries of mice. |
format |
article |
author |
Clare L. V. Westhorpe M. Ursula Norman Pam Hall Sarah L. Snelgrove Michaela Finsterbusch Anqi Li Camden Lo Zhe Hao Tan Songhui Li Susan K. Nilsson A. Richard Kitching Michael J. Hickey |
author_facet |
Clare L. V. Westhorpe M. Ursula Norman Pam Hall Sarah L. Snelgrove Michaela Finsterbusch Anqi Li Camden Lo Zhe Hao Tan Songhui Li Susan K. Nilsson A. Richard Kitching Michael J. Hickey |
author_sort |
Clare L. V. Westhorpe |
title |
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes |
title_short |
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes |
title_full |
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes |
title_fullStr |
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes |
title_full_unstemmed |
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes |
title_sort |
effector cd4+ t cells recognize intravascular antigen presented by patrolling monocytes |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af |
work_keys_str_mv |
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1718383202686468096 |