Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes

Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerular capillaries of mice.

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Autores principales: Clare L. V. Westhorpe, M. Ursula Norman, Pam Hall, Sarah L. Snelgrove, Michaela Finsterbusch, Anqi Li, Camden Lo, Zhe Hao Tan, Songhui Li, Susan K. Nilsson, A. Richard Kitching, Michael J. Hickey
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Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af
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spelling oai:doaj.org-article:22e1efaabd3040d59c9272c8e00fd9af2021-12-02T16:49:50ZEffector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes10.1038/s41467-018-03181-42041-1723https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03181-4https://doaj.org/toc/2041-1723Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerular capillaries of mice.Clare L. V. WesthorpeM. Ursula NormanPam HallSarah L. SnelgroveMichaela FinsterbuschAnqi LiCamden LoZhe Hao TanSonghui LiSusan K. NilssonA. Richard KitchingMichael J. HickeyNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Clare L. V. Westhorpe
M. Ursula Norman
Pam Hall
Sarah L. Snelgrove
Michaela Finsterbusch
Anqi Li
Camden Lo
Zhe Hao Tan
Songhui Li
Susan K. Nilsson
A. Richard Kitching
Michael J. Hickey
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
description Monocytes constitutively adhere and crawl along the glomerular endothelium and are thought to contribute to glomerulonephritis. Here the authors use multiphoton microscopy to show local antigen presentation by MHCII+ monocytes to T cells in glomerular capillaries of mice.
format article
author Clare L. V. Westhorpe
M. Ursula Norman
Pam Hall
Sarah L. Snelgrove
Michaela Finsterbusch
Anqi Li
Camden Lo
Zhe Hao Tan
Songhui Li
Susan K. Nilsson
A. Richard Kitching
Michael J. Hickey
author_facet Clare L. V. Westhorpe
M. Ursula Norman
Pam Hall
Sarah L. Snelgrove
Michaela Finsterbusch
Anqi Li
Camden Lo
Zhe Hao Tan
Songhui Li
Susan K. Nilsson
A. Richard Kitching
Michael J. Hickey
author_sort Clare L. V. Westhorpe
title Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
title_short Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
title_full Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
title_fullStr Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
title_full_unstemmed Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes
title_sort effector cd4+ t cells recognize intravascular antigen presented by patrolling monocytes
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/22e1efaabd3040d59c9272c8e00fd9af
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