Random amino acid mutations and protein misfolding lead to Shannon limit in sequence-structure communication.

The transmission of genomic information from coding sequence to protein structure during protein synthesis is subject to stochastic errors. To analyze transmission limits in the presence of spurious errors, Shannon's noisy channel theorem is applied to a communication channel between amino acid...

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Détails bibliographiques
Auteur principal: Andreas Martin Lisewski
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2008
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/22e56c9f285348d6b6f2b56b1322e013
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