Microevolution During Serial Mouse Passage Demonstrates <italic toggle="yes">FRE3</italic> as a Virulence Adaptation Gene in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>

ABSTRACT Passage in mice of opportunistic pathogens such as Cryptococcus neoformans is known to increase virulence, but little is known about the molecular mechanisms involved in virulence adaptation. Serial mouse passage of nine environmental strains of serotype A C. neoformans identified two highl...

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Autores principales: Guowu Hu, Shu Hui Chen, Jin Qiu, John E. Bennett, Timothy G. Myers, Peter R. Williamson
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/22e8109560514a0c9e4df231069c035e
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