Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor µ2 and capsid proteins

Mammalian reovirus (MRV) is a double-stranded RNA (dsRNA) virus that affects the gastrointestinal and respiratory tracts. Here, the authors present the 3.3 Å cryo-EM asymmetric reconstruction of transcribing MRV that reveals the organization of the dsRNA genome, RNA interaction with the polymerase c...

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Auteurs principaux: Muchen Pan, Ana L. Alvarez-Cabrera, Joon S. Kang, Lihua Wang, Chunhai Fan, Z. Hong Zhou
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/22f352c3fd614f9fbae6f2f2d0326311
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