Avicin D: a protein reactive plant isoprenoid dephosphorylates Stat 3 by regulating both kinase and phosphatase activities.

Avicins, a class of electrophilic triterpenoids with pro-apoptotic, anti-inflammatory and antioxidant properties, have been shown to induce redox-dependant post-translational modification of cysteine residues to regulate protein function. Based on (a) the cross-talk that occurs between redox and pho...

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Autores principales: Valsala Haridas, Goshi Nishimura, Zhi-Xiang Xu, Fiona Connolly, Margaret Hanausek, Zbigniew Walaszek, Robert Zoltaszek, Jordan U Gutterman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/22f6c5e5d2014997ade1aa67b4f2abc7
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