Avicin D: a protein reactive plant isoprenoid dephosphorylates Stat 3 by regulating both kinase and phosphatase activities.
Avicins, a class of electrophilic triterpenoids with pro-apoptotic, anti-inflammatory and antioxidant properties, have been shown to induce redox-dependant post-translational modification of cysteine residues to regulate protein function. Based on (a) the cross-talk that occurs between redox and pho...
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Auteurs principaux: | Valsala Haridas, Goshi Nishimura, Zhi-Xiang Xu, Fiona Connolly, Margaret Hanausek, Zbigniew Walaszek, Robert Zoltaszek, Jordan U Gutterman |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2009
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Sujets: | |
Accès en ligne: | https://doaj.org/article/22f6c5e5d2014997ade1aa67b4f2abc7 |
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