Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

The oligometastasis hypothesis suggests certain metastases are limited in extent and curable with focal therapies. Here they identify three integrated molecular subtypes of colorectal cancer liver metastasis, which complement clinical risk stratification to distinguish the subset of oligometastatic...

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Autores principales:	Sean P. Pitroda, Nikolai N. Khodarev, Lei Huang, Abhineet Uppal, Sean C. Wightman, Sabha Ganai, Nora Joseph, Jason Pitt, Miguel Brown, Martin Forde, Kathy Mangold, Lai Xue, Christopher Weber, Jeremy P. Segal, Sabah Kadri, Melinda E. Stack, Sajid Khan, Philip Paty, Karen Kaul, Jorge Andrade, Kevin P. White, Mark Talamonti, Mitchell C. Posner, Samuel Hellman, Ralph R. Weichselbaum
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/22f79936b0e641648e56509a01ce8a84
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spelling	oai:doaj.org-article:22f79936b0e641648e56509a01ce8a842021-12-02T14:41:17ZIntegrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis10.1038/s41467-018-04278-62041-1723https://doaj.org/article/22f79936b0e641648e56509a01ce8a842018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04278-6https://doaj.org/toc/2041-1723The oligometastasis hypothesis suggests certain metastases are limited in extent and curable with focal therapies. Here they identify three integrated molecular subtypes of colorectal cancer liver metastasis, which complement clinical risk stratification to distinguish the subset of oligometastatic patients.Sean P. PitrodaNikolai N. KhodarevLei HuangAbhineet UppalSean C. WightmanSabha GanaiNora JosephJason PittMiguel BrownMartin FordeKathy MangoldLai XueChristopher WeberJeremy P. SegalSabah KadriMelinda E. StackSajid KhanPhilip PatyKaren KaulJorge AndradeKevin P. WhiteMark TalamontiMitchell C. PosnerSamuel HellmanRalph R. WeichselbaumNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sean P. Pitroda Nikolai N. Khodarev Lei Huang Abhineet Uppal Sean C. Wightman Sabha Ganai Nora Joseph Jason Pitt Miguel Brown Martin Forde Kathy Mangold Lai Xue Christopher Weber Jeremy P. Segal Sabah Kadri Melinda E. Stack Sajid Khan Philip Paty Karen Kaul Jorge Andrade Kevin P. White Mark Talamonti Mitchell C. Posner Samuel Hellman Ralph R. Weichselbaum Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
description	The oligometastasis hypothesis suggests certain metastases are limited in extent and curable with focal therapies. Here they identify three integrated molecular subtypes of colorectal cancer liver metastasis, which complement clinical risk stratification to distinguish the subset of oligometastatic patients.
format	article
author	Sean P. Pitroda Nikolai N. Khodarev Lei Huang Abhineet Uppal Sean C. Wightman Sabha Ganai Nora Joseph Jason Pitt Miguel Brown Martin Forde Kathy Mangold Lai Xue Christopher Weber Jeremy P. Segal Sabah Kadri Melinda E. Stack Sajid Khan Philip Paty Karen Kaul Jorge Andrade Kevin P. White Mark Talamonti Mitchell C. Posner Samuel Hellman Ralph R. Weichselbaum
author_facet	Sean P. Pitroda Nikolai N. Khodarev Lei Huang Abhineet Uppal Sean C. Wightman Sabha Ganai Nora Joseph Jason Pitt Miguel Brown Martin Forde Kathy Mangold Lai Xue Christopher Weber Jeremy P. Segal Sabah Kadri Melinda E. Stack Sajid Khan Philip Paty Karen Kaul Jorge Andrade Kevin P. White Mark Talamonti Mitchell C. Posner Samuel Hellman Ralph R. Weichselbaum
author_sort	Sean P. Pitroda
title	Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
title_short	Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
title_full	Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
title_fullStr	Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
title_full_unstemmed	Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
title_sort	integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/22f79936b0e641648e56509a01ce8a84
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Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

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