High-throughput functional evaluation of BRCA2 variants of unknown significance
Many germline variants are found in the BRCA2 gene, some of which pre-dispose women to breast and ovarian cancer. Here, the authors develop a method to determine the functional significance of BRCA2 variants and show that it is comparable to the IARC system of classifying variants.
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/232e6a0f6eaf4785a36ff58421838450 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|