Atomic Force Microscopy micro-rheology reveals large structural inhomogeneities in single cell-nuclei

Abstract During growth, differentiation and migration of cells, the nucleus changes size and shape, while encountering forces generated by the cell itself and its environment. Although there is increasing evidence that such mechanical signals are employed to control gene expression, it remains uncle...

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Bibliographic Details
Main Authors: Michael Lherbette, Ália dos Santos, Yukti Hari-Gupta, Natalia Fili, Christopher P. Toseland, Iwan A. T. Schaap
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/238f6000e7a14ac5ab9064a834e36ab6
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