Bilateral Paraventricular Nucleus Upregulation of Extracellular Superoxide Dismutase Decreases Blood Pressure by Regulation of the NLRP3 and Neurotransmitters in Salt-Induced Hypertensive Rats

Aims: Long-term salt diet induces the oxidative stress in the paraventricular nucleus (PVN) and increases the blood pressure. Extracellular superoxide dismutase (Ec-SOD) is a unique antioxidant enzyme that exists in extracellular space and plays an essential role in scavenging excessive reactive oxy...

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Autores principales: Qing Su, Xiao-Jing Yu, Xiao-Min Wang, Hong-Bao Li, Ying Li, Juan Bai, Jie Qi, Nianping Zhang, Kai-Li Liu, Yan Zhang, Guo-Qing Zhu, Yu-Ming Kang
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/23bbe02bb51a4a1cbde2759576756c07
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