Structural Equation Modeling of In silico Perturbations

Gene expression is controlled by multiple regulators and their interactions. Data from genome-wide gene expression assays can be used to estimate molecular activities of regulators within a model organism and extrapolate them to biological processes in humans. This approach is valuable in studies to...

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Bibliographic Details
Main Authors: Jianying Li, Pierre R. Bushel, Lin Lin, Kevin Day, Tianyuan Wang, Francesco J. DeMayo, San-Pin Wu, Jian-Liang Li
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/23c0123353774a9faf428f930b51a0fc
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