Nucleosome positioning stability is a modulator of germline mutation rate variation across the human genome
Nucleosome organization has been suggested to affect local mutation rates in the genome. Here, the authors analyse data on >300,000 human de novo mutations and high-resolution nucleosome maps and provide evidence that nucleosome positioning stability modulates germline mutation rate variation acr...
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Autores principales: | , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2020
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Acceso en línea: | https://doaj.org/article/23ca1f57c02745bc969e2879df4387b6 |
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