Proteolytic Processing and Activation of <named-content content-type="genus-species">Clostridium perfringens</named-content> Epsilon Toxin by Caprine Small Intestinal Contents

ABSTRACT Epsilon toxin (ETX), a pore-forming toxin produced by type B and D strains of Clostridium perfringens, mediates severe enterotoxemia in livestock and possibly plays a role in human disease. During enterotoxemia, the nearly inactive ETX prototoxin is produced in the intestines but then must...

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Autores principales: John C. Freedman, Jihong Li, Francisco A. Uzal, Bruce A. McClane
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/23f4dcbff7d34740b15b94603f59458f
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