Proteolytic Processing and Activation of <named-content content-type="genus-species">Clostridium perfringens</named-content> Epsilon Toxin by Caprine Small Intestinal Contents
ABSTRACT Epsilon toxin (ETX), a pore-forming toxin produced by type B and D strains of Clostridium perfringens, mediates severe enterotoxemia in livestock and possibly plays a role in human disease. During enterotoxemia, the nearly inactive ETX prototoxin is produced in the intestines but then must...
Saved in:
Main Authors: | John C. Freedman, Jihong Li, Francisco A. Uzal, Bruce A. McClane |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2014
|
Subjects: | |
Online Access: | https://doaj.org/article/23f4dcbff7d34740b15b94603f59458f |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Evidence That VirS Is a Receptor for the Signaling Peptide of the <named-content content-type="genus-species">Clostridium perfringens</named-content> Agr-like Quorum Sensing System
by: Jihong Li, et al.
Published: (2020) -
The Potential Therapeutic Agent Mepacrine Protects Caco-2 Cells against <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin Action
by: John C. Freedman, et al.
Published: (2017) -
Bystander Host Cell Killing Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin
by: Archana Shrestha, et al.
Published: (2016) -
Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of <named-content content-type="genus-species">Clostridium perfringens</named-content> Enterotoxin
by: Archana Shrestha, et al.
Published: (2013) -
The VirS/VirR Two-Component System Regulates the Anaerobic Cytotoxicity, Intestinal Pathogenicity, and Enterotoxemic Lethality of <named-content content-type="genus-species">Clostridium perfringens</named-content> Type C Isolate CN3685
by: Menglin Ma, et al.
Published: (2011)