Alternative activation of macrophages and induction of arginase are not components of pathogenesis mediated by Francisella species.

Virulent Francisella tularensis ssp tularensis is an intracellular, Gram negative bacterium that causes acute lethal disease following inhalation of fewer than 15 organisms. Pathogenicity of Francisella infections is tied to its unique ability to evade and suppress inflammatory responses in host cel...

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Auteurs principaux: Amanda J Griffin, Deborah D Crane, Tara D Wehrly, Dana P Scott, Catharine M Bosio
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
Q
Accès en ligne:https://doaj.org/article/240a6df3c82d472697796ca7109b6c65
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