Circadian clock disruption by selective removal of endogenous carbon monoxide

Abstract Circadian rhythms are regulated by transcription-translation feedback loops (TTFL) of clock genes. Previous studies have demonstrated that core transcriptional factors, NPAS2 and CLOCK, in the TTFL can reversibly bind carbon monoxide (CO) in vitro. However, little is known about whether end...

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Autores principales: Saika Minegishi, Ikuko Sagami, Shigeru Negi, Koji Kano, Hiroaki Kitagishi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/24186bf1afc04da39932da7b83b32754
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