Cell-fate decision of mesenchymal stem cells toward osteocyte differentiation is committed by spheroid culture

Abstract Osteocytes are mechanosensory commander cells to regulate bone remodeling throughout the lifespan. While the osteocytes are known as terminally differentiated cells derived from mesenchymal stem cells, the detailed mechanisms of osteocyte differentiation remain unclear. In this study, we fa...

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Autores principales: Jeonghyun Kim, Taiji Adachi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2425ffd5bce84a2d9252cadcd93ffc76
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