Cell-fate decision of mesenchymal stem cells toward osteocyte differentiation is committed by spheroid culture

Abstract Osteocytes are mechanosensory commander cells to regulate bone remodeling throughout the lifespan. While the osteocytes are known as terminally differentiated cells derived from mesenchymal stem cells, the detailed mechanisms of osteocyte differentiation remain unclear. In this study, we fa...

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Bibliographic Details
Main Authors: Jeonghyun Kim, Taiji Adachi
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/2425ffd5bce84a2d9252cadcd93ffc76
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