PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor
Abstract The Published Kinase Inhibitor Set (PKIS) is a publicly-available chemogenomic library distributed to more than 300 laboratories by GlaxoSmithKline (GSK) between 2011 and 2015 and by SGC-UNC from 2015 to 2017. Screening this library of well-annotated, published kinase inhibitors has yielded...
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Auteurs principaux: | , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/2427271ceabc4a4d9e480023fca08c5f |
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