Interspecific germline transmission of cultured primordial germ cells.

In birds, the primordial germ cell (PGC) lineage separates from the soma within 24 h following fertilization. Here we show that the endogenous population of about 200 PGCs from a single chicken embryo can be expanded one million fold in culture. When cultured PGCs are injected into a xenogeneic embr...

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Autores principales: Marie-Cecile van de Lavoir, Ellen J Collarini, Philip A Leighton, Jeffrey Fesler, Daniel R Lu, William D Harriman, T S Thiyagasundaram, Robert J Etches
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/243d6e2898f243b7a3cec31eabb968bc
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