Interspecific germline transmission of cultured primordial germ cells.
In birds, the primordial germ cell (PGC) lineage separates from the soma within 24 h following fertilization. Here we show that the endogenous population of about 200 PGCs from a single chicken embryo can be expanded one million fold in culture. When cultured PGCs are injected into a xenogeneic embr...
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Autores principales: | Marie-Cecile van de Lavoir, Ellen J Collarini, Philip A Leighton, Jeffrey Fesler, Daniel R Lu, William D Harriman, T S Thiyagasundaram, Robert J Etches |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/243d6e2898f243b7a3cec31eabb968bc |
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