Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete

Abstract Treponema pallidum subsp. pallidum, the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate throughout the body. Identification of bacterial factors promoting dissemination is crucial for syphilis vaccine development. An important s...

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Main Authors: Wei-Chien Andrew Kao, Helena Pětrošová, Rhodaba Ebady, Karen V. Lithgow, Pablo Rojas, Yang Zhang, Yae-Eun Kim, Yae-Ram Kim, Tanya Odisho, Nupur Gupta, Annette Moter, Caroline E. Cameron, Tara J. Moriarty
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/24434a553c8f4861988c1a974bab078c
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