Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins
ABSTRACT Trypanosomatids (order Kinetoplastida), including the human pathogens Trypanosoma cruzi (agent of Chagas disease), Trypanosoma brucei, (African sleeping sickness), and Leishmania (leishmaniasis), affect millions of people and animals globally. T. cruzi is considered one of the least studied...
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Format: | article |
Langue: | EN |
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American Society for Microbiology
2017
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Accès en ligne: | https://doaj.org/article/24601f0528a048dc8f67bc65964beaaa |
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