Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses

Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses

Previously, a broadly neutralizing antibody, 3I14, active against groups 1 and 2 influenza A viruses was isolated from human memory B cells and showed protection in mice from lethal viral challenge. Here, Harshbarger and Deming et al. provide the crystal structure of 3I14 Fab in complex with H3, H6,...

Full description

Saved in:
Bibliographic Details
Main Authors: Wayne D. Harshbarger, Derrick Deming, Gordon J. Lockbaum, Nattapol Attatippaholkun, Maliwan Kamkaew, Shurong Hou, Mohan Somasundaran, Jennifer P. Wang, Robert W. Finberg, Quan Karen Zhu, Celia A. Schiffer, Wayne A. Marasco
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/246479680d0d43448f6a2d4b305f320c
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/246479680d0d43448f6a2d4b305f320c

Similar Items