Recapitulating the Angiogenic Switch in a Hydrogel-Based 3D In Vitro Tumor-Stroma Model
To ensure nutrient and oxygen supply, tumors beyond a size of 1–2 mm<sup>3</sup> need a connection to the vascular system. Thus, tumor cells modify physiological tissue homeostasis by secreting inflammatory and angiogenic cytokines. This leads to the activation of the tumor microenvironm...
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Autores principales: | , , |
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Formato: | article |
Lenguaje: | EN |
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MDPI AG
2021
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Acceso en línea: | https://doaj.org/article/246a956929554e52aebd565abee79c04 |
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