DNA accessibility of chromatosomes quantified by automated image analysis of AFM data

Abstract DNA compaction and accessibility in eukaryotes are governed by nucleosomes and orchestrated through interactions between DNA and DNA-binding proteins. Using QuantAFM, a method for automated image analysis of atomic force microscopy (AFM) data, we performed a detailed statistical analysis of...

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Autores principales: Martin Würtz, Dennis Aumiller, Lina Gundelwein, Philipp Jung, Christian Schütz, Kathrin Lehmann, Katalin Tóth, Karl Rohr
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/24a686c0245a404ebd42063bf6a81db9
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