In vitro RNase and nucleic acid binding activities implicate coilin in U snRNA processing.

Coilin is known as the marker protein for Cajal bodies (CBs), subnuclear domains important for the biogenesis of small nuclear ribonucleoproteins (snRNPs) which function in pre-mRNA splicing. CBs associate non-randomly with U1 and U2 gene loci, which produce the small nuclear RNA (snRNA) component o...

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Autores principales: Hanna J Broome, Michael D Hebert
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/24bd3892fa954e779668aadc02bce967
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