Rag2 Deficiency Enhances Susceptibility to Systemic Mouse Adenovirus Type 1 Infection

Introduction: Recombination-activating gene 1 (Rag1) and Rag2, which are essential in V(D)J recombination, play a crucial role in B and T cell maturation. Method: We investigated the effects of Rag2 deficiency in clustered regularly interspaced short palindromic repeats/Cas9-mediated FVB-Rag2 knocko...

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Autores principales: Han-Kyul Lee, Sun-Min Seo, Jun-Young Kim, Han-Woong Kim, Eui-Suk Jeong, Yang-Kyu Choi
Formato: article
Lenguaje:EN
Publicado: Karger Publishers 2021
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Acceso en línea:https://doaj.org/article/24c336e45690474090c0cfde561fb74c
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