A systemically deliverable Vaccinia virus with increased capacity for intertumoral and intratumoral spread effectively treats pancreatic cancer

Background Pancreatic cancer remains one of the most lethal cancers and is refractory to immunotherapeutic interventions. Oncolytic viruses are a promising new treatment option, but current platforms demonstrate limited efficacy, especially for inaccessible and metastatic cancers that require system...

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Autores principales: Jahangir Ahmed, Ming Yuan, Zhongxian Zhang, Nicholas Lemoine, Yaohe Wang, Giulia Marelli, Louisa S Chard Dunmall, Carmela Di Gioia, Jinxin Miao, Zhenguo Cheng, Rathi Gangeswaran
Formato: article
Lenguaje:EN
Publicado: BMJ Publishing Group 2021
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Acceso en línea:https://doaj.org/article/24cba0290a804cf7b8b7cccfb572b712
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