Implication of IRF4 aberrant gene expression in the acute leukemias of childhood.

The most frequent targets of genetic alterations in human leukemias are transcription factor genes with essential functions in normal blood cell development. The Interferon Regulatory Factor 4 (IRF4) gene encodes a transcription factor important for key developmental stages of hematopoiesis, with kn...

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Autores principales: Maria Adamaki, George I Lambrou, Anastasia Athanasiadou, Marianna Tzanoudaki, Spiros Vlahopoulos, Maria Moschovi
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/250db6a46789427f8069c577552efbe8
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