NOTCH-ing up nucleotide metabolism in T-cell acute lymphoblastic leukemia

In a recent issue of Science Advances, Srivastava et al. report a novel nucleotide biosynthesis regulatory role for UBR7 in NOTCH1-driven T-ALL. Here we will discuss their key findings and the implications for using cancer metabolism to understand the development and progression of T-ALL.

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Autor principal: Andrew Volk
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/251f1a27ee844af19641e05ddcf19a98
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