NOTCH-ing up nucleotide metabolism in T-cell acute lymphoblastic leukemia
In a recent issue of Science Advances, Srivastava et al. report a novel nucleotide biosynthesis regulatory role for UBR7 in NOTCH1-driven T-ALL. Here we will discuss their key findings and the implications for using cancer metabolism to understand the development and progression of T-ALL.
Guardado en:
Autor principal: | Andrew Volk |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/251f1a27ee844af19641e05ddcf19a98 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
T-Cell Acute Lymphoblastic Leukemia—Current Concepts in Molecular Biology and Management
por: Parveen Shiraz, et al.
Publicado: (2021) -
The influence of MTHFR genetic polymorphisms on methotrexate therapy in pediatric acute lymphoblastic leukemia
por: Shen Yaqing, et al.
Publicado: (2021) -
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
por: Ting Zhu, et al.
Publicado: (2021) -
Overcoming Microenvironment-Mediated Chemoprotection through Stromal Galectin-3 Inhibition in Acute Lymphoblastic Leukemia
por: Somayeh S. Tarighat, et al.
Publicado: (2021) -
Vision and Change–ing A First-Year Biology Classroom
por: Gail S. Begley
Publicado: (2012)