Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum.

Lipoic acid (LA) is an essential cofactor of alpha-keto acid dehydrogenase complexes (KADHs) and the glycine cleavage system. In Plasmodium, LA is attached to the KADHs by organelle-specific lipoylation pathways. Biosynthesis of LA exclusively occurs in the apicoplast, comprising octanoyl-[acyl carr...

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Autores principales: Svenja Günther, Lynsey Wallace, Eva-Maria Patzewitz, Paul J McMillan, Janet Storm, Carsten Wrenger, Ryan Bissett, Terry K Smith, Sylke Müller
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2007
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Acceso en línea:https://doaj.org/article/252a1ea7e85545459b36b533bd9436f1
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