Apicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparum.
Lipoic acid (LA) is an essential cofactor of alpha-keto acid dehydrogenase complexes (KADHs) and the glycine cleavage system. In Plasmodium, LA is attached to the KADHs by organelle-specific lipoylation pathways. Biosynthesis of LA exclusively occurs in the apicoplast, comprising octanoyl-[acyl carr...
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| Autores principales: | , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2007
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/252a1ea7e85545459b36b533bd9436f1 |
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