Expansion of myeloid-derived suppressor cells contributes to metabolic osteoarthritis through subchondral bone remodeling

Abstract Background Osteoarthritis (OA) subsequent to acute joint injury accounts for a significant proportion of all arthropathies. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells classically known for potent immune-suppressive activity; however,...

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Autores principales: Lixia Zhang, Cameron L. Kirkwood, Jiho Sohn, Ashley Lau, Mary Bayers-Thering, Supinder Kour Bali, Sridhar Rachala, John M. Marzo, Mark J. Anders, Frank Beier, Keith L. Kirkwood
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/25352de7e5a5423e8bab737e355eecad
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