Expansion of myeloid-derived suppressor cells contributes to metabolic osteoarthritis through subchondral bone remodeling

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Expansion of myeloid-derived suppressor cells contributes to metabolic osteoarthritis through subchondral bone remodeling

Abstract Background Osteoarthritis (OA) subsequent to acute joint injury accounts for a significant proportion of all arthropathies. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells classically known for potent immune-suppressive activity; however,...

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Détails bibliographiques
Auteurs principaux:	Lixia Zhang, Cameron L. Kirkwood, Jiho Sohn, Ashley Lau, Mary Bayers-Thering, Supinder Kour Bali, Sridhar Rachala, John M. Marzo, Mark J. Anders, Frank Beier, Keith L. Kirkwood
Format:	article
Langue:	EN
Publié:	BMC 2021
Sujets:	Osteoarthritis Myeloid-derived suppressor cells Osteoclasts Obesity Subchondral bone Diseases of the musculoskeletal system RC925-935
Accès en ligne:	https://doaj.org/article/25352de7e5a5423e8bab737e355eecad
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