PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.

<h4>Background</h4>Neuroblastoma (NB) is a severe pediatric tumor originating from neural crest derivatives and accounting for 15% of childhood cancer mortality. The heterogeneous and complex genetic etiology has been confirmed with the identification of mutations in two genes, encoding...

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Détails bibliographiques
Auteurs principaux: Tiziana Bachetti, Daniela Di Paolo, Simona Di Lascio, Valentina Mirisola, Chiara Brignole, Marta Bellotti, Irene Caffa, Chiara Ferraris, Michele Fiore, Diego Fornasari, Roberto Chiarle, Silvia Borghini, Ulrich Pfeffer, Mirco Ponzoni, Isabella Ceccherini, Patrizia Perri
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/25cdb8382a974c138a1f00865f9237ca
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Internet

https://doaj.org/article/25cdb8382a974c138a1f00865f9237ca

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