PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.

<h4>Background</h4>Neuroblastoma (NB) is a severe pediatric tumor originating from neural crest derivatives and accounting for 15% of childhood cancer mortality. The heterogeneous and complex genetic etiology has been confirmed with the identification of mutations in two genes, encoding...

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Autores principales: Tiziana Bachetti, Daniela Di Paolo, Simona Di Lascio, Valentina Mirisola, Chiara Brignole, Marta Bellotti, Irene Caffa, Chiara Ferraris, Michele Fiore, Diego Fornasari, Roberto Chiarle, Silvia Borghini, Ulrich Pfeffer, Mirco Ponzoni, Isabella Ceccherini, Patrizia Perri
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/25cdb8382a974c138a1f00865f9237ca
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https://doaj.org/article/25cdb8382a974c138a1f00865f9237ca

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