PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.
<h4>Background</h4>Neuroblastoma (NB) is a severe pediatric tumor originating from neural crest derivatives and accounting for 15% of childhood cancer mortality. The heterogeneous and complex genetic etiology has been confirmed with the identification of mutations in two genes, encoding...
Guardado en:
Autores principales: | Tiziana Bachetti, Daniela Di Paolo, Simona Di Lascio, Valentina Mirisola, Chiara Brignole, Marta Bellotti, Irene Caffa, Chiara Ferraris, Michele Fiore, Diego Fornasari, Roberto Chiarle, Silvia Borghini, Ulrich Pfeffer, Mirco Ponzoni, Isabella Ceccherini, Patrizia Perri |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
|
Materias: | |
Acceso en línea: | https://doaj.org/article/25cdb8382a974c138a1f00865f9237ca |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A Focus on Regulatory Networks Linking MicroRNAs, Transcription Factors and Target Genes in Neuroblastoma
por: Patrizia Perri, et al.
Publicado: (2021) -
Defining Pathological Activities of ALK in Neuroblastoma, a Neural Crest-Derived Cancer
por: Anna M. Wulf, et al.
Publicado: (2021) -
Targeting anaplastic lymphoma kinase (ALK) gene alterations in neuroblastoma by using alkylating pyrrole-imidazole polyamides.
por: Yoko Ota, et al.
Publicado: (2021) -
The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status
por: Ricky M. Trigg, et al.
Publicado: (2019) -
Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities
por: Mintu Chandra, et al.
Publicado: (2019)