Semiconductor photocatalysis to engineering deuterated N-alkyl pharmaceuticals enabled by synergistic activation of water and alkanols

Controllable deuteration of N-alkyl amines is crucial in drug-development as they constitute over 50% of the top-selling drugs. Here, the authors report a polymeric semiconductor acting as photocatalyst in water-splitting and in isotope alkanol-oxidation by photoexcited electron-hole pairs, and furn...

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Auteurs principaux: Zhaofei Zhang, Chuntian Qiu, Yangsen Xu, Qing Han, Junwang Tang, Kian Ping Loh, Chenliang Su
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/25ce76b9ead54c09be5c8a90ae0e434e
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