Molecular Response to Combined Molecular- and External Radiotherapy in Head and Neck Squamous Cell Carcinoma (HNSCC)

Molecular Response to Combined Molecular- and External Radiotherapy in Head and Neck Squamous Cell Carcinoma (HNSCC)

Combination treatment of molecular targeted and external radiotherapy is a promising strategy and was shown to improve local tumor control in a HNSCC xenograft model. To enhance the therapeutic value of this approach, this study investigated the underlying molecular response. Subcutaneous HNSCC FaDu...

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Autores principales: Treewut Rassamegevanon, Louis Feindt, Lydia Koi, Johannes Müller, Robert Freudenberg, Steffen Löck, Wiebke Sihver, Enes Çevik, Ariane Christel Kühn, Cläre von Neubeck, Annett Linge, Hans-Jürgen Pietzsch, Jörg Kotzerke, Michael Baumann, Mechthild Krause, Antje Dietrich
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
molecular targeted radiotherapy
DNA damage response
Cetuximab
cell death induction
external beam radiotherapy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/25dba7d79733444bab324fa7b79bf155
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https://doaj.org/article/25dba7d79733444bab324fa7b79bf155

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