New environment-sensitive multichannel DNA fluorescent label for investigation of the protein-DNA interactions.

Here, we report the study of a new multichannel DNA fluorescent base analogue 3-hydroxychromone (3HC) to evaluate its suitability as a fluorescent reporter probe of structural transitions during protein-DNA interactions and its comparison with the current commercially available 2-aminopurine (aPu),...

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Auteurs principaux: Alexandra A Kuznetsova, Nikita A Kuznetsov, Yuri N Vorobjev, Nicolas P F Barthes, Benoît Y Michel, Alain Burger, Olga S Fedorova
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
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Accès en ligne:https://doaj.org/article/25e756899cb94e80bdac07a9dbccbea3
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