New environment-sensitive multichannel DNA fluorescent label for investigation of the protein-DNA interactions.
Here, we report the study of a new multichannel DNA fluorescent base analogue 3-hydroxychromone (3HC) to evaluate its suitability as a fluorescent reporter probe of structural transitions during protein-DNA interactions and its comparison with the current commercially available 2-aminopurine (aPu),...
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Main Authors: | Alexandra A Kuznetsova, Nikita A Kuznetsov, Yuri N Vorobjev, Nicolas P F Barthes, Benoît Y Michel, Alain Burger, Olga S Fedorova |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/25e756899cb94e80bdac07a9dbccbea3 |
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