On the evolutionary origin of eukaryotic DNA methyltransferases and Dnmt2.

The Dnmt2 enzymes show strong amino acid sequence similarity with eukaryotic and prokaryotic DNA-(cytosine C5)-methyltransferases. Yet, Dnmt2 enzymes from several species were shown to methylate tRNA-Asp and had been proposed that eukaryotic DNA methyltransferases evolved from a Dnmt2-like tRNA meth...

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Autores principales: Tomasz P Jurkowski, Albert Jeltsch
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/25fa0e3bce5942a3a09fe4358c82431e
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