Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain
Human microglia present unique features; therefore, chimeric mouse models can enhance modelling of human microglia response in health and disease. Here, the authors show that hiPSC-derived mature microglia developed in the mouse brain, retain their identity and respond to demyelination.
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/263c025eeb5a4353bd524f6f00f63e13 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|