PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols
Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme involved in processes of cell cycle regulation, DNA repair, transcription, and replication. Hyperactivity of PARP-1 induced by changes in cell homeostasis promotes development of chronic pathological processes leading to cell death during v...
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Main Authors: | Natalya V. Maluchenko, Alexey V. Feofanov, Vasily M. Studitsky |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Subjects: | |
Online Access: | https://doaj.org/article/26611aef751b49b9ac76fbd4a016704f |
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