Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy

The development of resistance to endocrine therapy is a significant, clinical problem in breast cancer. Here, the authors identify a rare subpopulation of cells that drive resistance following transcriptional reprogramming.

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Bibliographic Details
Main Authors: Sung Pil Hong, Thalia E. Chan, Ylenia Lombardo, Giacomo Corleone, Nicole Rotmensz, Sara Bravaccini, Andrea Rocca, Giancarlo Pruneri, Kirsten R. McEwen, R. Charles Coombes, Iros Barozzi, Luca Magnani
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/266ee5cecff04b52b1a25a258b6d6db4
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